Primary pleural leiomyosarcoma with rapid progression and fatal outcome: a case report

Journal of Medical Case Reports, 05/08/2012

A 58–year–old North African man was admitted to the hospital with complaints of dyspnea and chest pain. Chest Computed tomography (CT) revealed right pleural effusion and pleural thickening. A trans–thoracic needle biopsy yielded a diagnosis of leiomyosarcoma with tumor cells strongly and uniformly positive for vimentin, a–smooth muscle actin at immunohistochemical analysis. A general examination did not show any metastatic lesions in other areas. One month after diagnosis, the tumor grew rapidly, with pulmonary invasion, and therefore he was treated only by palliative care. He died one month later from respiratory failure. Because no organ of origin of the leiomyosarcoma, other than the pleura, was detected, this case was diagnosed as a primary pleural leiomyosarcoma.

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