A series of patients on anti-TNF therapy referred to a multidisciplinary lung cancer service

Irish Journal of Medical Science, 05/01/2012

The series highlights the potential malignant risk of anti–TNF theraphy to a general medical audience.


  • Retrospective review of patients over an 18–month period who were referred to a multidisciplinary lung cancer service.


  • Three patients who underwent recent anti–TNF therapies and presented with solid organ tumours.
  • All had significant additional risks for cancer including smoking and family history and active connective tissue diseases with a past history of immunosuppressive therapies.

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