Serum MMP-8 levels increase in colorectal cancer and correlate with disease course and inflammatory properties of primary tumors

International Journal of Cancer, 05/01/2012

The results indicate that matrix metalloproteinases (MMPs) is involved in the course and progression of colorectal cancer (CRC) influencing the immune response against the tumor and contributing to the resolution of necrosis. Serum or plasma MMP–8 may prove to be a worthy biomarker for CRC.

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