Tumor microenvironment composition in pediatric classical Hodgkin lymphoma is modulated by age and Epstein-Barr virus infection

International Journal of Cancer, 04/23/2012

The results suggest that in Epstein–Barr virus (EBV)+Classical Hodgkin lymphoma (cHL) an effective immune response directed against viral or tumor antigens may be triggered in the tumor microenvironment and that physiological and age–related changes of the immune system may also modulate the tumor microenvironment in pediatric cHL.

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