Pretherapeutic Expression of the hOCT1 Gene Predicts a Complete Molecular Response to Imatinib Mesylate in Chronic-Phase Chronic Myeloid Leukemia

Acta Haematologica, 04/13/2012

The 5–year event–free and overall survival analyses revealed no significant differences between the groups. These data imply that knowledge of the pretherapeutic level of hOCT1 (human organic cation transporter 1) could be a useful marker to predict IM therapy outcome in treatment–na├»ve chronic–phase (CP) chronic myeloid leukemia (CML) patients.

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