Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer
International Journal of Cancer, 04/09/2012Innominato PF et al.
Chemotherapy disrupted circadian activity rhythm in nearly 50% of the patients. Circadian disruption on chemotherapy predicted for shorter overall survival. The prevention of chemotherapy–induced circadian disruption might reduce toxicity and improve efficacy in cancer patients.
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