Protein Z/protein Z-dependent protease inhibitor system in human non-small-cell lung cancer tissue
Thrombosis Research, 04/04/2012Sierko E et al.
Protein Z–dependent protease inhibitor and PZ expression in non–small–cell lung cancer (NSCLC) cells, Endothelial cells (ECs) and tumor infiltrating macrophages may suggest a role for PZ/ZPI in the anticoagulant mechanisms at the tumor site. The presence of F1+2 and fibrin, along with a disproportional expression of ZPI and PZ, might point to impaired function of the coagulation inhibitory system in NSCLC tissue.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.