Alcohol intake and mortality among women with invasive breast cancer
British Journal of Cancer, 01/05/2012
H R Harris et al. –These findings suggest that alcohol intake up to approximately one small drink per day does not negatively impact breast cancer–specific survival and a half drink per day is associated with a decreased risk of mortality from other causes.
Investigated whether alcohol intake was associated with survival among 3146 women diagnosed with invasive breast cancer in the Swedish Mammography Cohort
Alcohol consumption was estimated using food frequency questionnaire
Cox proportional hazard models were used to calculate HRs and 95% CIs
From 1987 to 2008 there were 385 breast cancer–specific deaths and 860 total deaths
No significant association was observed between alcohol intake and breast cancer–specific survival
Women who consumed 10?g per day (corresponding to approximately 0.75 to 1 drinks) or more of alcohol had an adjusted HR (95% CI) of breast cancer–specific death of 1.36 (0.82–2.26;ptrend=0.47) compared with non–drinkers
Significant inverse association was observed between alcohol and non–breast cancer deaths
Those who consumed 3.4–9.9?g per day of alcohol had a 33% lower risk of death compared with non–drinkers (95% CI 0.50–0.90;ptrend=0.04)
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