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A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in caucasians

Liu Q et al. – The results suggest that the rs12435998 single–nucleotide polymorphism (SNP) in SEL1L gene plays a role in modifying age at diagnosis of pancreatic ductal adenocarcinoma (PDA) in Caucasian nonsmokers. In addition, this SNP may serve as a prognostic marker in PDA patients who undergo the same or similar treatment as the clinical trials. [more...]