Oncology News Articles

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The latest Cancer and Oncology news articles published daily by MDLinx physician editors who comb through the top peer-reviewed clinical journals for the medical articles that will make a difference to you and your practice. Organized by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants can stay current on latest oncology topics, symptoms, treatments, risk factors in Cancer and Hematology.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): Results from the dose-finding portion of a phase 1/2 study The Lancet Oncology, September 18, 2014    Clinical Article

2 The management of acute adverse effects of breast cancer treatment in general practice: A Video-Vignette study Full Text Journal of Medical Internet Research, September 18, 2014    Clinical Article

3 Management of breast cancer patients with chemotherapy-induced neutropenia or febrile neutropenia Breast Care, September 18, 2014    Clinical Article

4 Extrapleural pneumonectomy in the treatment of epithelioid malignant pleural mesothelioma: novel prognostic implications of combined N1 and N2 nodal involvement based on experience in 529 patients Annals of Surgery, September 18, 2014    Review Article

5 Clinical practice guidelines for identification, screening and follow-up of individuals at high risk of primary cutaneous melanoma: A systematic review British Journal of Dermatology, September 18, 2014    Review Article    Clinical Guideline

6 The role of focal therapy in the management of localised prostate cancer: A systematic review Full Text European Urology, September 18, 2014    Evidence Based Medicine    Review Article

7 BRAF, MEK and KIT inhibitors for melanoma: Adverse events and their management Full Text Chinese Clinical Oncology, September 18, 2014    Review Article

8 Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients Nutrition and Cancer, September 18, 2014    Clinical Article

9 The influence of prior abiraterone treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer Full Text European Urology, September 18, 2014    Clinical Article

10 Total laparoscopic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: oncologic advantages over open approaches? Annals of Surgery, September 18, 2014    Review Article

11 Low PIAS3 expression in malignant mesothelioma is associated with increased STAT3 activation and poor patient survival Clinical Cancer Research, September 18, 2014    Clinical Article

12 Failure of evidence-based cancer care in the United States: the association between rectal cancer treatment, cancer center volume, and geography Annals of Surgery, September 18, 2014    Clinical Article

13 Extent of surgery for papillary thyroid cancer is not associated with survival: an analysis of 61,775 patients Annals of Surgery, September 18, 2014    Clinical Article

14 Association of variants in genes related to the immune response and obesity with BPH in CLUE II Prostate Cancer & Prostatic Diseases, September 18, 2014    Clinical Article

15 WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner Journal of Experimental Medicine, September 18, 2014    Clinical Article

16 Anti-CCR4 monoclonal antibody mogamulizumab for the treatment of EBV-associated T- and NK-cell lymphoproliferative diseases Clinical Cancer Research, September 18, 2014    Clinical Article

17 Comparison of two platelet transfusion strategies to minimize ABO-nonidentical transfusion, outdating, and shortages using a computer-simulated "virtual blood bank" Transfusion, September 18, 2014    Clinical Article

18 Five-year cumulative incidence of invasive anal cancer among HIV-infected patients according to baseline anal cytology results: An inception cohort analysis HIV Medicine, September 18, 2014    Clinical Article

19 Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: Implications for PEGylated arginine deiminase combination therapy Full Text BMC Cancer, September 18, 2014    Clinical Article

20 The interleukin-10-1082A>G polymorphism and lymphoma risk: A meta-analysis Cancer Biomarkers, September 18, 2014    Evidence Based Medicine

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Clinical Pearls in Oncology

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Highlights in Oncology

VPAC1 overexpression associated with colon cancer aggression

As reported in Tumor Biology, VPAC1 expression is increased in poorly differentiated compared to well-differentiated colon cancer. VPAC1 expression is also increased in the blood vessels and macrophages adjacent to colon cancer tissues compared to healthy tissues. The overexpression of VPAC1 is related to EGFR overexpression.

CHD7 associated with survival in pancreatic ductal adenocarcinoma patients receiving gemcitabine

As reported in Cancer Research, low CHD7 expression is associated with increased RFS and OS in pancreatic ductal adenocarcinoma patients receiving gemcitabine. There was no association between CHD7 expression and RFS or OS in patients who were not treated with gemcitabine.

YKL-40 predicts poor prognosis for bladder cancer

As reported in Urologic Oncology, the gene expression and serum level of YKL-40 are higher in patients with bladder cancer than healthy controls. Serum YKL-40 levels predict poor prognosis in patients with muscle-invasive bladder cancer (HR=1.75).

Other Topics in Oncology

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