Oncology News & Articles

1 Neoadjuvant chemotherapy and bevacizumab for HER2-negative breast cancer New England Journal of Medicine, January 27, 2012    Clinical Article

2 Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): A phase 3 open-label, randomized controlled trial The Lancet, January 27, 2012    Clinical Article

3 A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: Development and international validation studies The Lancet - Early Online Publication, January 27, 2012

4 Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy Full Text BMC Cancer, January 27, 2012

5 Identification of a biomarker panel for colorectal cancer diagnosis Full Text BMC Cancer, January 27, 2012    Clinical Article

6 Age determines the prognostic role of the cancer stem cell marker aldehyde dehydrogenase-1 in breast cancer Full Text BMC Cancer, January 27, 2012

7 Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics Full Text BMC Cancer, January 27, 2012

8 Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosis Full Text BMC Cancer, January 27, 2012

9 Immunoglobulin free light chain levels and recovery from myeloma kidney on treatment with chemotherapy and high cut-off haemodialysis Nephrology Dialysis Transplantation, January 27, 2012

10 Low dose rituximab in adult patients with idiopathic autoimmune hemolytic anemia: clinical efficacy and biological studies Blood, January 27, 2012    Clinical Article

11 Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort Blood, January 27, 2012

12 A phase 2 study of the safety, tolerability and pharmacodynamics of FBS0701, a novel oral iron chelator, in transfusional iron overload Blood, January 27, 2012

13 Asthma and coagulation Blood, January 27, 2012

14 Trastuzumab for treatment of refractory/relapsed HER2-positive adult B-ALL Blood, January 27, 2012    Clinical Article

15 Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma Blood, January 27, 2012    Clinical Article

16 RNAi screening of the kinome with cytarabine in leukemias Blood, January 27, 2012
Exclusive Author Commentary

17 JAK inhibitors for myeloproliferative neoplasms Blood, January 27, 2012

18 Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors preserving normal stem cells Blood, January 27, 2012

19 Thrombocythemia and polycythemia in patients younger than 20 years at diagnosis: clinical and biological features, treatment, and long-term outcome Blood, January 27, 2012

20 A clinically relevant population of leukemic CD34+CD38- cells in acute myeloid leukemia Blood, January 27, 2012

Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies Journal of Thoracic Disease, 08/05/2011

1 ABVD alone versus radiation-based therapy in limited-stage Hodgkins lymphoma New England Journal of Medicine, December 13, 2011

2 Randomized Phase III Study of Surgery Alone or Surgery Plus Preoperative Cisplatin and Gemcitabine in Stages IB to IIIA Non-Small-Cell Lung Cancer Journal of Clinical Oncology, December 1, 2011

3 Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomized trials The Lancet, November 11, 2011

4 Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer: A meta-analysis of randomized trials JAMA, December 7, 2011

5 Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer New England Journal of Medicine, December 9, 2011

6 Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial The Lancet, December 2, 2011

7 Beam: A randomized phase II study evaluating the activity of bevacizumab in combination with carboplatin plus paclitaxel in patients with previously untreated advanced melanoma Journal of Clinical Oncology, December 1, 2011

8 Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100,000 women in 123 randomized trials The Lancet - Early Online Publication, December 6, 2011

9 Accelerated partial breast irradiation using brachytherapy for breast cancer: Patterns in utilization and guideline concordance Journal of the National Cancer Institute, December 19, 2011

10 Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: A randomised, phase 3 trial The Lancet, December 16, 2011

11 Prospective assessment of outcomes in 411 patients treated with hyperbaric oxygen for chronic radiation tissue injury Cancer, December 7, 2011

12 Long-term follow-up of high-dose chemotherapy with autologous stem-cell transplantation and response-adapted whole-brain radiotherapy for newly diagnosed primary CNS lymphoma: Results of the multicenter Ostdeutsche Studiengruppe Hämatologie und Onkologie OSHO-53 phase II study Annals of Oncology, December 7, 2011

13 Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer Journal of Clinical Oncology, November 2, 2011

14 Phase III trial comparing capecitabine plus cisplatin versus capecitabine plus cisplatin with concurrent capecitabine radiotherapy in completely resected gastric cancer with D2 lymph node dissection: The ARTIST trial Journal of Clinical Oncology, December 21, 2011

15 Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment Journal of Cancer Research & Clinical Oncology, December 5, 2011

16 Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: Preliminary safety results from the CHHiP randomised controlled trial The Lancet Oncology - Online First, December 13, 2011

17 Evaluation of oral chemotherapy with capecitabine and cyclophosphamide plus thalidomide and prednisone in prostate cancer patients Journal of Cancer Research & Clinical Oncology, December 5, 2011

18 Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): An open-label randomized phase 3 trial The Lancet, November 28, 2011

19 Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer New England Journal of Medicine, December 9, 2011

20 Docetaxel/irinotecan combination chemotherapy in platinum/taxane-refractory and -resistant ovarian cancer: JGOG/WJGOG Intergroup Study International Journal of Clinical Oncology, December 5, 2011