Anti-emetic effect of midazolam added to morphine patient-controlled analgesia after total abdominal hysterectomy
Anesthesia and Intensive Care, 06/07/2010
Huh BK et al. – Nausea and vomiting are frequent adverse effects of patient–controlled analgesia with opioids. This study was designed to compare the effect of midazolam to that of ondansetron for prevention of nausea and vomiting during morphine patient–controlled analgesia...Midazolam is as effective as ondansetron in preventing opioid–induced nausea and vomiting following total abdominal hysterectomy and has acceptable side–effects.