Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
Your Unread Messages in Obstetrics & Gynecology
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D Scott Cunningham MD, PhD
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UAE more effective than myomectomy for leiomyomas
1 Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling The Journal of Pathology, June 20, 2013 Clinical Article
2 Health-related quality of life among patients with ovarian cancer at Mulago Hospital, Uganda International Journal of Gynecology & Obstetrics, June 20, 2013 Clinical Article
3 Ovarian cancer symptom awareness and anticipated time to help-seeking for symptoms among UK women Journal of Family Planning & Reproductive Health Care, June 20, 2013 Clinical Article
4 It depends on how the relationship was before you became ill: Black South African womens experiences of life partner support through the trajectory of cervical cancer European Journal of Cancer Care, June 20, 2013 Review Article
5 Outcomes and patterns of secondary relapse in platinum-sensitive ovarian cancer: Implications for tertiary cytoreductive surgery European Journal of Surgical Oncology, June 20, 2013 Clinical Article
6 Levonorgestrel-releasing intrauterine system for atypical endometrial hyperplasia Cochrane Reviews, June 20, 2013 Evidence Based Medicine
7 Hormonal and Reproductive Risk Factors for Sporadic Microsatellite Stable and Unstable Endometrial Tumors Cancer Epidemiology, Biomarkers & Prevention, June 20, 2013 Clinical Article
8 Molecular pathogenesis of endometrial cancers in patients with Lynch syndrome Cancer, June 20, 2013 Clinical Article
9 Prolactin-induced protein (pip) regulates proliferation of luminal a type breast cancer cells in an estrogen-independent manner PLOS ONE, June 20, 2013 Review Article
10 Role of activated rac1/cdc42 in mediating endothelial cell proliferation and tumor angiogenesis in breast cancer PLOS ONE, June 20, 2013 Review Article
11 Profibrotic interleukin-33 is correlated with uterine leiomyoma tumour burden Human Reproduction, June 20, 2013 Clinical Article
12 Diagnostic accuracy of hand-assisted laparoscopy in predicting resectability of peritoneal carcinomatosis from gynecological malignancies European Journal of Surgical Oncology, June 20, 2013 Clinical Article
13 Prognostic value of the number and laterality of metastatic inguinal lymph nodes in vulvar cancer: Revisiting the FIGO staging system European Journal of Surgical Oncology, June 20, 2013 Clinical Article
14 Accuracy of MDCT in the preoperative definition of Peritoneal Cancer Index (PCI) in patients with advanced ovarian cancer who underwent peritonectomy and hyperthermic intraperitoneal chemotherapy (HIPEC) Abdominal Imaging , June 20, 2013 Clinical Article
15 Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy Cancer Research, June 20, 2013 Clinical Article
16 PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer Clinical and Translational Oncology, June 20, 2013 Clinical Article
17 Efficacy of combined levonorgestrel-releasing intrauterine system with gonadotropin-releasing hormone analog for the treatment of adenomyosis Full Text Medical Principles and Practice, June 20, 2013
18 Fertility preservation in young females with non-gynaecologic malignancy: an emerging speciality Irish Journal of Medical Science, June 20, 2013 Evidence Based Medicine
19 miR-375 is upregulated in acquired paclitaxel resistance in cervical cancer British Journal of Cancer, June 19, 2013 Clinical Article
20 Non-sex cord-stromal ovarian tumors frequently produce and secrete estrogen in postmenopausal women: impact on bone metabolism and abnormal endometrial histology Journal of Clinical Endocrinology and Metabolism, June 19, 2013 Review Article
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBased on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryIn a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summaryIndexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
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