Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
Your Unread Messages in Obstetrics & Gynecology
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D Scott Cunningham MD, PhD
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UAE more effective than myomectomy for leiomyomas
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Running from that pile of unread journals?
401 Cervical cancer screening: What’s new and what’s coming? Cleveland Clinic Journal of Medicine, March 19, 2013
402 A cross-sectional analysis of lower genital tract intraepithelial neoplasia in immune-compromised women with an abnormal Pap Archives of Gynecology and Obstetrics, March 19, 2013 Clinical Article
403 Body mass index (BMI) and breast cancer: impact on tumor histopatologic features, cancer subtypes and recurrence rate in pre and postmenopausal women Gynecological Endocrinology, March 19, 2013 Clinical Article
404 Stages I to II WHO 2003–defined low-grade endometrial stromal sarcoma: How much primary therapy is needed and how little is enough? International Journal of Gynecological Cancer, March 19, 2013 Clinical Article
405 Endoloop ligation technique for prolapsed pedunculated submucous uterine myoma: utility and reliability Archives of Gynecology and Obstetrics, March 19, 2013 Review Article
406 Large or persistent lymphocyst increases the risk of lymphedema, lymphangitis, and deep vein thrombosis after retroperitoneal lymphadenectomy for gynecologic malignancy Archives of Gynecology and Obstetrics, March 19, 2013 Clinical Article
407 TP53 codon 72 polymorphism and risk of cervical carcinoma in Serbian women Archives of Gynecology and Obstetrics, March 19, 2013 Clinical Article
408 Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma Cochrane Reviews, March 19, 2013 Clinical Article
409 Agreement for tumor grade of ovarian carcinoma: analysis of archival tissues from the surveillance, epidemiology, and end results residual tissue repository Cancer Causes and Control, March 19, 2013 Review Article
410 Prevalence of type-specific human papillomavirus and pap results in Chinese women: a multi-center, population-based cross-sectional study Cancer Causes and Control, March 19, 2013 Review Article Clinical Article
411 Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models Cancer Chemotherapy and Pharmacology, March 19, 2013 Clinical Article
412 Uptake and Outcomes of Intensity-Modulated Radiation Therapy for Uterine Cancer Gynecologic Oncology, March 19, 2013 Clinical Article
413 Impact of beta blocker medication in patients with platinum sensitive recurrent ovarian cancer- a combined analysis of 2 prospective multicenter trials by the AGO Study Group, NCIC-CTG and EORTC-GCG Gynecologic Oncology, March 19, 2013 Clinical Article
414 High level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcome Gynecologic Oncology, March 19, 2013 Clinical Article
415 Uterine cervical carcinoma: a comparison of two- and three-dimensional T2-weighted turbo spin-echo MR imaging at 3.0 T for image quality and local-regional staging European Radiology, March 19, 2013 Clinical Article
416 Pelvic Peritonectomy without Intraperitoneal Chemotherapy for Localized Peritoneal Carcinomatosis Anticancer Research, March 19, 2013 Clinical Article
417 Promoter methylation of DAPK1, FHIT, MGMT, and CDKN2A genes in cervical carcinoma International Journal of Clinical Oncology, March 19, 2013 Clinical Article
418 Preoperative clinical and radiological features of metastatic ovarian tumors Archives of Gynecology and Obstetrics, March 18, 2013 Clinical Article
419 Current concepts in the imaging of uterine sarcoma Abdominal Imaging , March 18, 2013 Review Article
420 Proven non-carriers in BRCA families have an earlier age of onset of breast cancer European Journal of Cancer, March 18, 2013 Clinical Article
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBased on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryIn a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summary1 Pre-treatment surgical para-aortic lymph node assessment in locally advanced cervical cancer Cochrane Reviews, April 3, 2013
2 High-grade vaginal intraepithelial neoplasia: can we be selective about who we treat? BJOG: An International Journal of Obstetrics and Gynaecology, April 4, 2013
3 Current role of robotic hysterectomy Journal of Gynecologic Surgery, April 25, 2013
4 Surgical technique to prevent spillage of cyst fluid during operation for cystic ovarian tumors Pediatric Surgery International, March 1, 2013
5 Robotic single-site hysterectomy (RSS-H) vs. laparoendoscopic single-site hysterectomy (LESS-H) in early endometrial cancer: A double-Institution case-control study Gynecologic Oncology, April 15, 2013
6 Screening for gynecological cancers Expert Review of Obstetrics & Gynecology, April 18, 2013 Review Article
7 Early detection of ovarian cancer American Journal of Obstetrics and Gynecology, April 18, 2013 Review Article
8 Systemic treatment for recurrent epithelial ovarian cancer Expert Review of Obstetrics & Gynecology, April 17, 2013 Review Article
9 The role of the fallopian tube in the origin of ovarian cancer American Journal of Obstetrics and Gynecology, April 17, 2013
10 Fertility drug use and the risk of ovarian tumors in infertile women: a case-control study Fertility and Sterility, April 3, 2013
11 Accuracy of Positron Emission Tomography/Computed Tomography in the Diagnosis and Restaging for Recurrent Ovarian Cancer: A Meta-Analysis International Journal of Gynecological Cancer, April 29, 2013 Evidence Based Medicine Review Article
12 Comparison of sandwich chemo-radiotherapy and six cycles of chemotherapy followed by adjuvant radiotherapy in patients with stage IIIC endometrial cancer: a single center experience Archives of Gynecology and Obstetrics, April 8, 2013
13 Disparities in Ovarian Cancer Care Quality and Survival According to Race and Socioeconomic Status Journal of the National Cancer Institute, April 8, 2013 Review Article
14 Controversies of the Hormonal Conservative Treatment of Endometrial Cancer Gynecologic and Obstetric Investigation, April 12, 2013 Review Article
15 Colposcopically directed cervical biopsy during pregnancy; minor surgical and obstetrical complications and high rates of persistence and regression Acta Obstetricia et Gynecologica Scandinavica, April 19, 2013
16 Impact of lymphadenectomy in uterine endometrioid carcinoma European Journal of Surgical Oncology, March 11, 2013 Review Article
17 Patterns of care for locally advanced vulvar cancer American Journal of Obstetrics and Gynecology, March 26, 2013 Review Article
18 Epidemiology and Investigations for Suspected Endometrial Cancer Journal of Obstetrics and Gynaecology Canada, April 11, 2013 Free full text Clinical Guideline
19 Predictive value of serum HE4 and CA125 concentrations in endometrial carcinoma American Journal of Obstetrics and Gynecology, April 17, 2013
20 Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trial European Journal of Obstetrics & Gynecology and Reproductive Biology, March 29, 2012
Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
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