Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
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D Scott Cunningham MD, PhD
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UAE more effective than myomectomy for leiomyomas
141 Elective birth at 37 weeks of gestation versus standard care for women with an uncomplicated twin pregnancy at term: the Twins Timing of Birth Randomised Trial Full Text BJOG: An International Journal of Obstetrics and Gynaecology, September 7, 2012 Clinical Article
142 Usefulness of hook wire localization biopsy under imaging guidance for nonpalpable breast lesions detected radiologically Full Text International Journal of Women's Health, September 7, 2012 Clinical Article
143 Gonorrhea treatment guidelines revised by CDC Full Text OBG Management, September 6, 2012 Clinical Article
144 Enhancing breast milk production with Domperidone in mothers of preterm neonates (empower trial) Full Text BMC Pregnancy and Childbirth, September 6, 2012 Clinical Article
145 Clinical role of bisphosphonate therapy Full Text International Journal of Women's Health, September 6, 2012 Clinical Article
146 Prevalence and risk factors of childbirth-related post-traumatic stress symptoms Full Text BMC Pregnancy and Childbirth, September 5, 2012 Clinical Article
147 Bowel perforation secondary to illegally induced abortion: a tertiary hospital experience in Tanzania Full Text World Journal of Emergency Surgery, September 5, 2012
148 Comparison Of The Anesthetic Effects Of Intrathecal Levobupivacaine + Fentanyl And Bupivacaine + Fentanyl During Caesarean Section Full Text Middle East Journal of Anesthesiology, September 4, 2012 Clinical Article
149 Usefulness of hook wire localization biopsy under imaging guidance for nonpalpable breast lesions detected radiologically Full Text Clinical Interventions in Aging, September 4, 2012
150 De novo achondroplasia causing four consecutive unsuccessful pregnancies: a case report Full Text Journal of Medical Case Reports, September 4, 2012
151 Cost-Effectiveness of Maternal Treatment to Prevent Perinatal Hepatitis B Virus Transmission Full Text Obstetrics and Gynecology, September 3, 2012 Original Publication Date: September 2, 2011
152 Dysregulation of Placental Endothelial Lipase in Obese Women With Gestational Diabetes Mellitus Full Text Diabetes, September 2, 2012 Original Publication Date: September 1, 2011
153 Mortality rates among early-stage hormone receptor–positive breast cancer patients: A population-based cohort study in Denmark Full Text Journal of the National Cancer Institute, September 2, 2012 Original Publication Date: September 1, 2011
154 Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: Results from the NSABP P-1 and D-2 clinical trials Full Text Clinical Cancer Research, September 2, 2012 Original Publication Date: September 1, 2011 Clinical Article
155 microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer Full Text Cancer Research, September 2, 2012 Original Publication Date: September 1, 2011
156 Dicer-Mediated Upregulation of BCRP Confers Tamoxifen Resistance in Human Breast Cancer Cells Full Text Clinical Cancer Research, September 1, 2012 Original Publication Date: August 31, 2011 Clinical Article
157 Randomized Phase II Trial of Letrozole plus Anti-MUC1 Antibody AS1402 in Hormone Receptor-positive Locally Advanced or Metastatic Breast Cancer Full Text Clinical Cancer Research, September 1, 2012 Original Publication Date: August 31, 2011
158 Dietary fat and breast cancer: comparison of results from food diaries and food-frequency questionnaires in the UK Dietary Cohort Consortium Full Text American Journal of Clinical Nutrition, September 1, 2012 Original Publication Date: August 31, 2011
159 Timing of Copper Intrauterine Device Insertion After Medical Abortion: A Randomized Controlled Trial Full Text Obstetrics and Gynecology, August 31, 2012 Original Publication Date: August 30, 2011
160 Can We Use Common Clinical Parameters to Identify Patients Who Will Need Insulin Treatment in Gestational Diabetes Full Text Diabetes Care, August 31, 2012 Original Publication Date: August 30, 2011
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBased on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryIn a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summary1 Coffee and caffeine intake and breast cancer risk: An updated dose-response meta-analysis of 37 published studies Gynecologic Oncology, May 10, 2013 Evidence Based Medicine
2 Comparative evaluation of 50 microgram oral misoprostol and 25 microgram intravaginal misoprostol for induction of labour at term: a randomized trial Journal of Obstetrics and Gynaecology Canada, May 13, 2013 Free full text
3 Probiotics in pregnancy and maternal outcomes: a systematic review The Journal of Maternal-Fetal and Neonatal Medicine, May 28, 2013
4 Plasma Vitamin D levels, menopause, and risk of breast cancer: dose-response meta-analysis of prospective studies Medicine, May 14, 2013
5 Techniques to reduce shoulder pain after laparoscopic surgery for benign gynaecological disease: a systematic review Gynecological Surgery, April 30, 2013 Review Article
6 The effects of soy consumption before diagnosis on breast cancer survival: the multiethnic cohort study Nutrition and Cancer, May 16, 2013
7 Loop Electrosurgical Excision Procedure and the Risk for Preterm Delivery Obstetrics and Gynecology, April 26, 2013
8 Maternal Obesity and Pre-Pregnancy Folic Acid Supplementation Obesity Facts, May 2, 2013
9 Maternal position during caesarean section for preventing maternal and neonatal complications Cochrane Reviews, April 3, 2013
10 What is the optimal threshold of serum Anti-Müllerian hormone (AMH) necessary for IVM treatments? Journal of Assisted Reproduction and Genetics, May 8, 2013
11 Early-pregnancy maternal vitamin D status and maternal hyperglycaemia Diabetic Medicine, May 15, 2013
12 Evaluation of the effect of omega-3 fatty acids in the treatment of premenstrual syndrome: A pilot trial Complementary Therapies in Medicine, May 9, 2013
13 Randomized Comparison of Uterine Artery Embolization (UAE) with Surgical Treatment in Patients with Symptomatic Uterine Fibroids (REST Trial): Subanalysis of 5-Year MRI Findings Cardiovascular and Interventional Radiology, May 9, 2013
14 Antibiotics for mastitis in breastfeeding women Cochrane Reviews, March 8, 2013 Review Article
15 Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes American Journal of Obstetrics and Gynecology, April 15, 2013
16 Management of pain associated with the insertion of intrauterine contraceptives Human Reproduction Update, May 16, 2013 Review Article
17
Reduction of the use of antimicrobial drugs following the rapid detection of Streptococcus agalactiae in the vagina at delivery by real-time PCR assay
BJOG: An International Journal of Obstetrics and Gynaecology, May 10, 2013
Exclusive Author Commentary
18
Pregnancy Loss and Later Risk of Atherosclerotic Disease
Circulation, May 1, 2013
Exclusive Author Commentary
19 Independent and combined effects of dietary weight loss and exercise on leukocyte telomere length in postmenopausal women Obesity, May 6, 2013
20 Association between weight gain during pregnancy and postpartum weight retention and obesity: a bias-adjusted meta-analysis Nutrition Reviews, May 7, 2013
Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
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