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Obstetrics & Gynecology News & Articles
Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
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Articles
Latest (73) Full Text Articles (1689)521 The Effect of Manipulation of the Programmed Intermittent Bolus Time Interval and Injection Volume on Total Drug Use for Labor Epidural Analgesia: A Randomized Controlled Trial Full Text Anesthesia & Analgesia, April 9, 2012 Original Publication Date: April 8, 2011
522 Associations of gestational weight gain with maternal body mass index, waist circumference, and blood pressure measured 16 y after pregnancy: the Avon Longitudinal Study of Parents and Children Full Text American Journal of Clinical Nutrition, April 9, 2012 Original Publication Date: April 8, 2011
523 Fetal Programming of Adult Disease: Implications for Prenatal Care Full Text Obstetrics and Gynecology, April 9, 2012 Original Publication Date: April 8, 2011
524 In utero and intra-partum HIV-1 transmission and acute HIV-1 infection during pregnancy: using the BED capture enzyme-immunoassay as a surrogate marker for acute infection Full Text International Journal of Epidemiology, April 9, 2012 Original Publication Date: April 8, 2011
525 Urine Screening for Chlamydia trachomatis During Pregnancy Full Text Obstetrics and Gynecology, April 8, 2012 Original Publication Date: April 7, 2011
526 Unfavorable Hormonal, Metabolic, and Inflammatory Alterations Persist after Menopause in Women with PCOS Full Text Journal of Clinical Endocrinology and Metabolism, April 8, 2012 Original Publication Date: April 7, 2011
527 Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis Full Text Clinical Cancer Research, April 8, 2012 Original Publication Date: April 7, 2011
528 Adjuvant Trastuzumab in HER2-Positive Breast Cancer Full Text New England Journal of Medicine, April 8, 2012 Original Publication Date: October 7, 2011
529 Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse - A European Pooled Analysis Full Text Clinical Cancer Research, April 7, 2012 Original Publication Date: April 6, 2011
530 Management of aromatase inhibitor-associated bone loss in postmenopausal women with breast cancer: Practical guidance for prevention and treatment Full Text Annals of Oncology, April 6, 2012 Original Publication Date: April 5, 2011 Clinical Article
531 Prevalence of autoimmune thyroid dysfunction in postpartum psychosis Full Text British Journal of Psychiatry, April 5, 2012 Original Publication Date: April 4, 2011 Clinical Article
532 Progesterone receptor isoform-specific promoter methylation - Association of PRA methylation with worse outcome in breast cancer patients. Full Text Clinical Cancer Research, April 5, 2012 Original Publication Date: April 4, 2011
533 Systematic CPG islands methylation profiling of genes in the WNT pathway in epithelial ovarian cancer identifies biomarkers of progression-free survival Full Text Clinical Cancer Research, April 5, 2012 Original Publication Date: April 4, 2011
534 Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 Study Full Text Journal of Clinical Oncology, April 3, 2012 Original Publication Date: March 2, 2011 Clinical Article
535 GnRH agonist for triggering of final oocyte maturation: time for a change of practice Full Text Human Reproduction Update, April 2, 2012 Original Publication Date: April 1, 2011
536 Prevalence, Natural History, and Clinical Outcome of Mild to Moderate Ventriculomegaly Full Text Obstetrics and Gynecology, April 2, 2012 Original Publication Date: April 1, 2011
537 Effects of Maternal Obesity on Tissue Concentrations of Prophylactic Cefazolin During Cesarean Delivery Full Text Obstetrics and Gynecology, April 2, 2012 Original Publication Date: April 1, 2011
538 Bilateral Oophorectomy in Relation to Risk of Postmenopausal Breast Cancer: Confounding by Nonmalignant Indications for Surgery Full Text American Journal of Epidemiology, April 2, 2012 Original Publication Date: April 1, 2011
539 Effect of Maternal Heart Disease on Fetal Growth Full Text Obstetrics and Gynecology, April 2, 2012 Original Publication Date: April 1, 2011
540 Advances in embryo culture platforms: novel approaches to improve preimplantation embryo development through modifications of the microenvironment Full Text Human Reproduction Update, April 2, 2012 Original Publication Date: April 1, 2011
Clinical Pearls in Obstetrics & Gynecology
- Maternal pneumococcal vaccination while pregnant has not been shown to reduce pneumococcal colonization in infants
- Children delivered via Cesarean have a two-fold increased risk of developing childhood obesity compared to those delivered vaginally
- Early diphtheria–tetanus–pertussis (DTP) vaccination is associated with increased mortality for low birth weight infant girls, but not boys
Highlights in Obstetrics & Gynecology
Antiseptics and antibiotics have similar efficacy in treatment of BV
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBRCA2 mutations improve OS in ovarian cancer patients
Based on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryTrans fat intake increases risk of ischemic stroke in postmenopausal women
In a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summaryMost Popular Obstetrics & Gynecology Articles
Last month's top read Top Articles of 20121 Maternal position during caesarean section for preventing maternal and neonatal complications Cochrane Reviews, April 3, 2013
2 The relationship of serum anti-Mullerian hormone with polycystic ovarian morphology and polycystic ovary syndrome: a prospective cohort study Human Reproduction, April 4, 2013
3 Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes American Journal of Obstetrics and Gynecology, April 15, 2013
4 Antibiotics for mastitis in breastfeeding women Cochrane Reviews, March 8, 2013 Review Article
5 Loop Electrosurgical Excision Procedure and the Risk for Preterm Delivery Obstetrics and Gynecology, April 26, 2013
6 Methods of term labour induction for women with a previous caesarean section Cochrane Reviews, April 1, 2013 Review Article
7 Consequences of a Primary Elective Cesarean Delivery Across the Reproductive Life Obstetrics and Gynecology, April 5, 2013
8 Laparoscopic tubal re-anastomosis versus in vitro fertilization: cost- based decision analysis American Journal of Obstetrics and Gynecology, April 18, 2013
9 Current role of robotic hysterectomy Journal of Gynecologic Surgery, April 25, 2013
10 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, March 29, 2013
11 Potential effects of updated pap test screening guidelines and adenocarcinoma in situ of the cervix Obstetrics and Gynecology, March 26, 2013
12 Menopause, estrogens and frailty Gynecological Endocrinology, April 16, 2013
13 Tachysystole in term labor: incidence, risk factors, outcomes, and effect on fetal heart tracings American Journal of Obstetrics and Gynecology, April 9, 2013
14 Cervical cancer screening: What’s new and what’s coming? Cleveland Clinic Journal of Medicine, March 19, 2013
15 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
16 Efficacy and Safety of Desvenlafaxine Treatment for Hot Flashes Associated with Menopause: A Meta-Analysis of Randomized Controlled Trials Gynecologic and Obstetric Investigation, April 12, 2013 Evidence Based Medicine Review Article
17 2012 Cervical Cancer Screening Guidelines and the Future Role of HPV Testing Clinical Obstetrics and Gynecology, February 4, 2013 Clinical Guideline
18 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study British Medical Journal, April 23, 2013 Free full text
19 Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer New England Journal of Medicine, April 2, 2013
20 Light drinking versus abstinence in pregnancy-behavioural and cognitive outcomes in 7-year-old children: a longitudinal cohort study BJOG: An International Journal of Obstetrics and Gynaecology, April 18, 2013
Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
Other Topics in Obstetrics & Gynecology
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