Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
Your Unread Messages in Obstetrics & Gynecology
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D Scott Cunningham MD, PhD
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UAE more effective than myomectomy for leiomyomas
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281 The effect of crystalloid versus Low molecular weight colloid solution on post-operative nausea and vomiting after ambulatory gynecological surgery - a prospective randomized trial Full Text BMC Anesthesiology, August 2, 2012
282 HIV-infected women do not have an elevated risk of cervical cancer. Full Text OBG Management, August 2, 2012 Clinical Article
283 Body mass and DNA promoter methylation in breast tumors in the Western New York Exposures and Breast Cancer Study Full Text American Journal of Clinical Nutrition, August 2, 2012 Original Publication Date: August 1, 2011
284 A Prospective Cohort Study of the Prevalence of Growth, Facial, and Central Nervous System Abnormalities in Children with Heavy Prenatal Alcohol Exposure. Full Text OBG Management, August 2, 2012 Clinical Article
285 Anesthetic review of emergency peripartum hysterectomy following vaginal and cesarean delivery: a retrospective study Full Text Korean Journal of Anesthesiology, August 2, 2012
286 The kidney in pregnancy: A journey of three decades Full Text Indian Journal of Nephrology, August 2, 2012
287 Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures Full Text BMC Cancer, August 2, 2012
288 Factors associated with acceptability of child adoption as a management option for infertility among women in a developing country Full Text International Journal of Women's Health, August 1, 2012
289 Bevacizumab added to neoadjuvant chemotherapy for breast cancer Full Text New England Journal of Medicine, July 31, 2012 Original Publication Date: February 2, 2012 Clinical Article
290 High-throughput mammographic density measurement: a tool for risk prediction of breast cancer Full Text Breast Cancer Research, July 31, 2012
291 Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line Full Text Investigational New Drugs, July 31, 2012
292 Timing of Delivery After External Cephalic Version and the Risk for Cesarean Delivery Full Text Obstetrics and Gynecology, July 30, 2012 Original Publication Date: July 29, 2011
293 Oxytocin Regimen for Labor Augmentation, Labor Progression, and Perinatal Outcomes Full Text Obstetrics and Gynecology, July 30, 2012 Original Publication Date: July 29, 2011
294 Early Breastfeeding Experiences and Postpartum Depression Full Text Obstetrics and Gynecology, July 30, 2012 Original Publication Date: July 29, 2011
295 Mammographic Density, Response to Hormones, and Breast Cancer Risk Full Text Journal of Clinical Oncology, July 30, 2012 Original Publication Date: June 29, 2011
296 Impact of estradiol-valerate dienogest on work productivity and activities of daily living in European and Australian women with heavy menstrual bleeding. Full Text International Journal of Women's Health, July 30, 2012 Clinical Article
297 Secondary Somatic Mutations Restoring BRCA1/2 Predict Chemotherapy Resistance in Hereditary Ovarian Carcinomas Full Text Journal of Clinical Oncology, July 30, 2012 Original Publication Date: June 29, 2011
298
Standardization of Estrogen Receptor Measurement in Breast Cancer Suggests False-Negative Results Are a Function of Threshold Intensity Rather Than Percentage of Positive Cells Full Text
Journal of Clinical Oncology, July 30, 2012
Original Publication Date: June 29, 2011
Exclusive Author Commentary
299 Association of Hormone-Related Characteristics and Breast Cancer Risk by Estrogen Receptor/Progesterone Receptor Status in the Shanghai Breast Cancer Study Full Text American Journal of Epidemiology, July 30, 2012 Original Publication Date: July 29, 2011
300 Silencing of Apoptosis-Inducing factor and poly(ADP-ribose) glycohydrolase reveals novel roles in breast cancer cell death after chemotherapy Full Text Molecular Cancer, July 30, 2012
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBased on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryIn a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summary1 Maternal position during caesarean section for preventing maternal and neonatal complications Cochrane Reviews, April 3, 2013
2 The relationship of serum anti-Mullerian hormone with polycystic ovarian morphology and polycystic ovary syndrome: a prospective cohort study Human Reproduction, April 4, 2013
3 Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes American Journal of Obstetrics and Gynecology, April 15, 2013
4 Antibiotics for mastitis in breastfeeding women Cochrane Reviews, March 8, 2013 Review Article
5 Loop Electrosurgical Excision Procedure and the Risk for Preterm Delivery Obstetrics and Gynecology, April 26, 2013
6 Methods of term labour induction for women with a previous caesarean section Cochrane Reviews, April 1, 2013 Review Article
7 Consequences of a Primary Elective Cesarean Delivery Across the Reproductive Life Obstetrics and Gynecology, April 5, 2013
8 Laparoscopic tubal re-anastomosis versus in vitro fertilization: cost- based decision analysis American Journal of Obstetrics and Gynecology, April 18, 2013
9 Current role of robotic hysterectomy Journal of Gynecologic Surgery, April 25, 2013
10 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, March 29, 2013
11 Potential effects of updated pap test screening guidelines and adenocarcinoma in situ of the cervix Obstetrics and Gynecology, March 26, 2013
12 Menopause, estrogens and frailty Gynecological Endocrinology, April 16, 2013
13 Tachysystole in term labor: incidence, risk factors, outcomes, and effect on fetal heart tracings American Journal of Obstetrics and Gynecology, April 9, 2013
14 Cervical cancer screening: What’s new and what’s coming? Cleveland Clinic Journal of Medicine, March 19, 2013
15 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
16 Efficacy and Safety of Desvenlafaxine Treatment for Hot Flashes Associated with Menopause: A Meta-Analysis of Randomized Controlled Trials Gynecologic and Obstetric Investigation, April 12, 2013 Evidence Based Medicine Review Article
17 2012 Cervical Cancer Screening Guidelines and the Future Role of HPV Testing Clinical Obstetrics and Gynecology, February 4, 2013 Clinical Guideline
18 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study British Medical Journal, April 23, 2013 Free full text
19 Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer New England Journal of Medicine, April 2, 2013
20 Light drinking versus abstinence in pregnancy-behavioural and cognitive outcomes in 7-year-old children: a longitudinal cohort study BJOG: An International Journal of Obstetrics and Gynaecology, April 18, 2013
Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
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