Where else but MDLinx OB/GYN can you find all the literature published in over 2,000 top peer-reviewed medical journals, ranked and summarized for you every 24 hours? Our team of physician editors is dedicated to keeping you current in less than 5 minutes a day. We cover the entirety of your diverse specialty, with subspecialty topics chosen to address the information needs of the entire women’s healthcare team, including gynecologic oncology, maternal-fetal medicine, obstetric and gynecologic surgery, ped/adolescent gynecology, repro/endo and infertility, the breast, menopausal medicine, diagnostic imaging, and much more.
Also find bonus content on this page that includes articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, that are “must-read.” Additionally, because Maintenance of Certification (MOC) is always a concern, we will provide some of the recent clinical pearls related to Obstetrics & Gynecology from our Smartest Doc and Physician Review quizzes, many of which result from a collaboration with the Cleveland Clinic Center for Continuing Education.
Your Unread Messages in Obstetrics & Gynecology
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1 Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer Full Text BMC Cancer, May 20, 2013 Clinical Article
2 Phase I dose-escalation study and population pharmacokinetic analysis of fixed dose rate gemcitabine plus carboplatin as second-line therapy in patients with ovarian cancer Gynecologic Oncology, May 20, 2013 Clinical Article
3 Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. a trial of the NCIC clinical trials group (NCIC CTG IND 199) Gynecologic Oncology, May 20, 2013 Clinical Article
4 Maternal Dietary Patterns are Associated With Risk of Neural Tube and Congenital Heart Defects American Journal of Epidemiology, May 20, 2013 Review Article
5 Value of urodynamics before stress urinary incontinence surgery: a randomized controlled trial Obstetrics and gynecology, May 20, 2013 Clinical Article
6 Measures of cardiovascular risk and subclinical atherosclerosis in a cohort of women with a remote history of preeclampsia Atherosclerosis, May 20, 2013 Clinical Article
7 Overdiagnosis in breast cancer screening: the importance of length of observation period and lead time Breast Cancer Research, May 20, 2013 Clinical Article
8 Loss of dok2 induces carboplatin resistance in ovarian cancer via suppression of apoptosis Gynecologic Oncology, May 20, 2013 Clinical Article
9 Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907 Breast Cancer Research and Treatment, May 20, 2013 Clinical Article
10 Detection of disseminated tumor cells in locally advanced breast cancer patients before primary systemic therapy The Breast, May 20, 2013 Clinical Article
11 Patients Anastrozole Compliance to Therapy (PACT) Program: Baseline Data and Patient Characteristics from a Population-Based, Randomized Study Evaluating Compliance to Aromatase Inhibitor Therapy in Postmenopausal Women with Hormone-Sensitive Early Breast Cancer Breast Care, May 20, 2013 Clinical Article
12 Role of Galactography in the Early Diagnosis of Breast Cancer Breast Care, May 20, 2013 Review Article
13 Effect of Endocrine Therapy on Quality of Life and Cognitive Functions in Patients with Breast Cancer Breast Care, May 20, 2013 Review Article
14 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors Obstetrics and gynecology, May 20, 2013 Clinical Article
15 Symptomatic local anaesthetic toxicity and plasma ropivacaine concentrations after transversus abdominis plane block for Caesarean section British Journal of Anesthesia, May 20, 2013 Clinical Article
16 Persistent antiphospholipid antibodies do not contribute to adverse pregnancy outcomes Rheumatology, May 20, 2013 Review Article
17 Postdiagnosis supplement use and breast cancer prognosis in the After Breast Cancer Pooling Project Breast Cancer Research and Treatment, May 20, 2013 Clinical Article
18 Is it safe and efficacious for women with lymphedema secondary to breast cancer to lift heavy weights during exercise: a randomised controlled trial Journal of Cancer Survivorship, May 20, 2013 Clinical Article
19 Position of the spanish menopause society regarding the management of menopausal symptoms in breast cancer patients Maturitas, May 20, 2013 Clinical Article
20 Breast Implant Procedures under Conscious Sedation: A 6-Year Experience in 461 Consecutive Patients Plastic and Reconstructive Surgery, May 20, 2013 Clinical Article
Based on a review article published in BMC Infectious Diseases, it has been concluded that antiseptics have equal efficacy to antibiotics in the treatment of bacterial vaginosis. The literature search covered the time period 1966-2010. Benzydamine, chlorhexidine, and polyhexamethylene niguanide were as effective as metronidazole and clindamycin in the short-term treatment of bacterial vaginosis.
Read the article summaryBased on an observational study orchestrated by researchers at the M D Anderson Cancer Center, BRCA2 mutations have been associated with improved survival in patients with high-grade serous ovarian cancer. The 5-year OS in patients with BRCA2 mutations was 61% compared with 25% for patients with BRCA wild-type. The 3-year PFS in patients with BRCA2 mutations was 44% compared with 16% for patients with BRCA wild-type. Patients with BRCA2 mutations exhibited 100% chemosensitivity compared to 82% and 80% for patients with BRCA wild-type and BRCA1 mutations, respectively. Genomic analysis of the tumors from patients with BRCA2 mutations suggested a “mutator phenotype” compared to tumors from patients with BRCA1 mutations.
Read the article summaryIn a study involving 87,025 postmenopausal women, those in the highest quintile of dietary trans fat had an increased risk of ischemic stroke (HR=1.39). In 663,041 person-years of follow-up, 1049 incident cases of ischemic stroke were reported. The effect was attenuated in aspirin users (HR=0.95) compared to non-users (HR=1.66).
Read the article summary1 Maternal position during caesarean section for preventing maternal and neonatal complications Cochrane Reviews, April 3, 2013
2 The relationship of serum anti-Mullerian hormone with polycystic ovarian morphology and polycystic ovary syndrome: a prospective cohort study Human Reproduction, April 4, 2013
3 Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes American Journal of Obstetrics and Gynecology, April 15, 2013
4 Antibiotics for mastitis in breastfeeding women Cochrane Reviews, March 8, 2013 Review Article
5 Loop Electrosurgical Excision Procedure and the Risk for Preterm Delivery Obstetrics and Gynecology, April 26, 2013
6 Methods of term labour induction for women with a previous caesarean section Cochrane Reviews, April 1, 2013 Review Article
7 Consequences of a Primary Elective Cesarean Delivery Across the Reproductive Life Obstetrics and Gynecology, April 5, 2013
8 Laparoscopic tubal re-anastomosis versus in vitro fertilization: cost- based decision analysis American Journal of Obstetrics and Gynecology, April 18, 2013
9 Current role of robotic hysterectomy Journal of Gynecologic Surgery, April 25, 2013
10 Randomized trial of Metformin versus Insulin in the Management of Gestational Diabetes American Journal of Obstetrics and Gynecology, March 29, 2013
11 Potential effects of updated pap test screening guidelines and adenocarcinoma in situ of the cervix Obstetrics and Gynecology, March 26, 2013
12 Menopause, estrogens and frailty Gynecological Endocrinology, April 16, 2013
13 Tachysystole in term labor: incidence, risk factors, outcomes, and effect on fetal heart tracings American Journal of Obstetrics and Gynecology, April 9, 2013
14 Cervical cancer screening: What’s new and what’s coming? Cleveland Clinic Journal of Medicine, March 19, 2013
15 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
16 Efficacy and Safety of Desvenlafaxine Treatment for Hot Flashes Associated with Menopause: A Meta-Analysis of Randomized Controlled Trials Gynecologic and Obstetric Investigation, April 12, 2013 Evidence Based Medicine Review Article
17 2012 Cervical Cancer Screening Guidelines and the Future Role of HPV Testing Clinical Obstetrics and Gynecology, February 4, 2013 Clinical Guideline
18 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study British Medical Journal, April 23, 2013 Free full text
19 Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer New England Journal of Medicine, April 2, 2013
20 Light drinking versus abstinence in pregnancy-behavioural and cognitive outcomes in 7-year-old children: a longitudinal cohort study BJOG: An International Journal of Obstetrics and Gynaecology, April 18, 2013
Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecology more
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