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Nexplanon, a radiopaque etonogestrel implant in combination with a next-generation applicator: 3-year results of a noncomparative multicenter trial.
American Journal of Obstetrics and Gynecology, 08/20/2012
Clinical Article
Mommers E et al. – This study investigates the efficacy, safety, removal characteristics, and X–ray visibility of Nexplanon, a radiopaque etonogestrel contraceptive implant combined with a next–generation applicator. It was seen that Nexplanon showed high contraceptive efficacy, palpability prior to removal, short removal times, and few removal complications. Nexplanon provides clinicians with a long–term hormonal contraceptive method with a safety and efficacy profile comparable to Implanon, radiopacity, and a new applicator.
Methods- A 3–year, non–comparative, multicenter study in women aged 18–40 years at 23 clinical sites
- A 3–year, non–comparative, multicenter study in women aged 18–40 years at 23 clinical sites
- Of 301 women who had an implant inserted, none became pregnant while the implant was in situ.
- Serious adverse events were reported in 16/301 (5.3%) women; none was judged as drug–related.
- Fibrosis around the implant was the most common removal complication (4.4%).
- The implant was visible on X–ray and palpable before removal with a mean removal time of 2 minutes.
