The importance of HER2 signaling in the tumor-initiating cell population in aromatase inhibitor-resistant breast cancer
Breast Cancer Research and Treatment, 08/17/2012
Gilani RA et al. – The results suggest that reducing or eliminating the TIC subpopulation with agents that target BCRP, HER2, human epidermal growth factor receptor 1 (EGFR2/HER1), and/or their downstream kinase pathways could be effective in preventing and/or treating acquired AI resistance.



