Resource allocation in utero and health in later life.
Barker D.J.P et al. – The way that a fetus obtains and allocates nutritional resources has profound consequences for its life–long health. Under the new developmental model for the origins of chronic disease, the causes to be identified are linked to normal variations in the processes of feto–placental development, that are associated with differences in the supply of nutrients to the baby. These differences programme the function of a few key systems that are linked to chronic disease, including the immune system, anti–oxidant defences, inflammation, and the number and quality of stem cells. There is not a separate cause for each different disease. Which chronic disease originates during development may depend more on timing than on qualitative differences in experience.