The IgG autoimmune response in postpartum acquired hemophilia A targets mainly the A1a1 domain of FVIII

Journal of Thrombosis and Haemostasis, 07/16/2012

The findings support the involvement of the Th1–driven response in the generation of autoantibodies in women with postpartum Acquired hemophilia A (AHA) compared to the other groups of AHA patients in whom production of Th2–driven IgG4 was predominant.

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