HGFK1 inhibits bone metastasis in breast cancer through the TAK1/p38 MAPK signaling pathway
Cancer Gene Therapy, 07/11/2012
Yao Y et al. – This study shows for the first time that HGFK1 significantly inhibits the metastasis of breast cancer to bone by activating the TAK1/p38 MAPK signaling pathway and inhibiting RANK expression. Thus, AAV–HGFK1 treatment represents a potential therapy for bone metastasis in breast cancer.