Adipose tissue and breast epithelial cells: A dangerous dynamic duo in breast cancer
Cancer Letters, 06/22/2012
Wang YY et al. – Two particular clinical aspects are addressed: obesity that was identified as an independent negative prognostic factor in breast cancer and the oncological safety of autologous fat transfer used in reconstructive surgery for breast cancer patients. This is preceded by the overall description of adipose tissue composition and function with special emphasis on the specificity of adipose depots and the species differences, key experimental aspects that need to be taken in account when cancer is considered.