Molecular subtype is determinant on inflammatory status and immunological profile from invasive breast cancer patients
Cancer Immunology, Immunotherapy, 06/08/2012
Herrera ACSA et al. – Triple–negative subtype exhibited the most aggressive profile of disease behavior, with reduction in both TNF–α and TGF–β, with high levels of lipid peroxidation and NO. The clinical importance of the findings lies in the fact that the inflammatory status varies in distinct ways due to molecular subtype of breast cancer, opening potential therapeutic targets to future therapies.