CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival

Clinical and Experimental Metastasis, 05/25/2012

The CD44+/CD24- phenotype in ovarian cancer cells demonstrate cancer stem cell–like properties of enhanced differentiation, invasion, and resistance to chemotherapy. This CD44+/CD24- phenotype correlates to clinical endpoints with increased risk of recurrence and shorter progression–free survival in patients with ovarian cancer.

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