CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival
Clinical and Experimental Metastasis, 05/25/2012
Meng E et al. – The CD44+/CD24- phenotype in ovarian cancer cells demonstrate cancer stem cell–like properties of enhanced differentiation, invasion, and resistance to chemotherapy. This CD44+/CD24- phenotype correlates to clinical endpoints with increased risk of recurrence and shorter progression–free survival in patients with ovarian cancer.