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Ibuprofen prophylaxis for levonorgestrel-releasing intrauterine system insertion: a randomized controlled trial
Contraception, 05/08/2012
Clinical Article
Chor J et al. – Administration of ibuprofen prophylaxis for levonorgestrel–releasing intrauterine system (LNG–IUS) insertion does not decrease pain at the time of insertion.
Methods- Authors conducted a double–blind, placebo–controlled trial, randomizing women to 800 mg ibuprofen or placebo 45 min prior to LNG–IUS insertion to determine effect of ibuprofen on the pain of LNG–IUS insertion.
- Eighty–one women completed the study: 44 received ibuprofen, and 37 received placebo.
- Women in the ibuprofen and placebo groups had similar mean scores for anticipated pain (4.07 and 3.91, respectively; p=.79), pain with tenaculum placement (3.86 and 3.81, respectively; p=.90) and pain with insertion (3.69 and 3.34, respectively; p=.91).
