The dynamic change of circulating tumour cells in patients with operable breast cancer before and after chemotherapy based on a multimarker QPCR platform
British Journal of Cancer, Exclusive Author Commentary

Chong MH et al. – Systemic adjuvant chemotherapy had a significant impact on circulating tumour cells (CTC) status, and this effect could be observed after three cycles of chemotherapy. Circulating tumour cells detection had the potential to be used to evaluate the efficacy of systemic adjuvant chemotherapy immediately after the chemotherapy was finished in operable breast cancer patients.

Following View Author Commentary page

The possible presence of hematogenous dissemination is the rationale behind the use of adjuvant chemotherapy in operable breast cancer patients. Circulating tumour cells (CTC) in peripheral blood may represent the early hematogenous dissemination of breast cancer. It was hypothesized CTC could be used to evaluate the efficacy of adjuvant chemotherapy immediately after chemotherapy was finished. So we conducted this trial. Factually it shew systemic adjuvant chemotherapy had a significant impact on CTC status, and this effect could be observed after three cycles of chemotherapy, CTC detection had the potential to be used to evaluate the efficacy of systemic adjuvant immediately after chemotherapy was finished. However, owing to the short follow-up time, our results should be interpreted with caution until verified from a long-term follow-up aimed to prognosis.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Obstetrics & Gynecology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Obstetrics & Gynecology Articles

1 A revised birth weight reference for the United States Obstetrics and Gynecology, July 14, 2014    Clinical Article

2 Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: A randomized controlled trial American Journal of Clinical Nutrition, July 17, 2014    Clinical Article

3 Metformin in reproductive health, pregnancy and gynaecological cancer: Established and emerging indications Human Reproduction Update, July 24, 2014    Review Article

4 First trimester coffee and tea intake and risk of gestational diabetes mellitus: A study within a national birth cohort BJOG: An International Journal of Obstetrics and Gynaecology, July 7, 2014    Clinical Article

5 Seafood consumption and umbilical cord blood mercury concentrations in a multiethnic maternal and child health cohort Full Text BMC Pregnancy and Childbirth, July 3, 2014    Free full text    Clinical Article

6 A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis American Journal of Obstetrics and Gynecology, July 2, 2014    Clinical Article

7 Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS Metabolism, July 22, 2014    Clinical Article

8 High-dose vaginal metronidazole for recurrent bacterial vaginosis: A pilot study Journal of Lower Genital Tract Disease, April 3, 2014    Clinical Article

9 Partly replacing meat protein with soy protein alters insulin resistance and blood lipids in postmenopausal women with abdominal obesity The Journal of Nutrition, July 23, 2014    Clinical Article

10 Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: A systematic review BJOG: An International Journal of Obstetrics and Gynaecology, June 5, 2014    Evidence Based Medicine    Review Article

11 The effect of chromium supplementation on polycystic ovary syndrome in adolescents Journal of Pediatric and Adolescent Gynecology , May 30, 2014    Clinical Article

12 Rate of low vitamin D levels in a low-risk obstetric population Journal of Midwifery and Women's Health, July 1, 2014    Clinical Article

13 Soy food and isoflavone intake and endometrial cancer risk: The Japan Public Health Center-based prospective study BJOG: An International Journal of Obstetrics and Gynaecology, June 30, 2014    Clinical Article

14 Oophorectomy and hysterectomy and cancer incidence in the cancer prevention study-II nutrition cohort Obstetrics and Gynecology, June 4, 2014    Clinical Article

15 Physical activity in pregnancy and neonatal body composition: The healthy start study Obstetrics and Gynecology, July 30, 2014    Clinical Article

16 Effects of yoga on arm volume among women with breast cancer related lymphedema: A pilot study Journal of Bodywork & Movement Therapies , July 15, 2014    Clinical Article

17 Mode of delivery in women with class III obesity: Planned cesarean compared to induction of labor American Journal of Obstetrics and Gynecology, July 7, 2014    Clinical Article

18 Vitamin D and menopause-A narrative review Maturitas, June 25, 2014    Review Article

19 Prospective association between red and processed meat intakes and breast cancer risk: modulation by an antioxidant supplementation in the SU.VI.MAX randomized controlled trial International Journal of Epidemiology, July 8, 2014    Clinical Article

20 Association between labetalol use for hypertension in pregnancy and adverse infant outcomes European Journal of Obstetrics & Gynecology and Reproductive Biology, February 17, 2014    Clinical Article

Indexed Journals in Obstetrics & Gynecology: Obstetrics and Gynecology, American Journal of Obstetrics and Gynecologymore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close