Treatment of Breast Cancer Cells by IGF1R Tyrosine Kinase Inhibitor Combined with Conventional Systemic Drugs
Anticancer Research, 04/10/2012
Hartog H et al. – Antagonistic effects should be anticipated when IGF1R inhibitors are combined with conventional systemic drugs in a subset of breast tumors. Development of functional biomarkers predicting tumor response to tailored insulin–like growth factor–1 receptor (IGF1R) therapy is warranted.