Testosterone pellet implants and migraine headaches: A pilot study

Maturitas, 03/23/2012

Continuous testosterone was effective therapy in reducing the severity of migraine headaches in both pre– and post–menopausal women.

Methods

  • Twenty–seven women with a history of documented migraine headache were asked to rate their headache severity using a five–point scale at baseline (prior to therapy); and again, 3months following treatment with testosterone implants. Improvement in headache severity was noted by 92% of patients and the mean level of improvement was statistically significant (3.3 on a 5 point scale).
  • Improvement in headache severity was noted by 92% of patients and the mean level of improvement was statistically significant (3.3 on a 5 point scale).

Results

  • There was no difference in the level of improvement between pre– and post–menopausal cohorts.
  • Seventy–four percent of patients reported a headache severity score of ‘0’ (none) on testosterone implant therapy for the 3–month treatment period.

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