Racial Disparities in the Association Between Gestational Diabetes Mellitus and Risk of Type 2 Diabetes
Journal of Women's Health, 05/17/2012Wang Y et al.
A history of gestational diabetes mellitus (GDM) is a strong predictor of subsequent type 2 diabetes among Louisiana women, especially among African American women.
Authors studied 1,142 women with a history of GDM and 18,856 women without a history of GDM aged 13–50 years with their first record of pregnancy in Louisiana State University Hospital–Based Longitudinal Study database between 1990 and 2009.
History of GDM was used to predict incident type 2 diabetes.
During a mean follow–up of 8.6 years, 1,394 women developed type 2 diabetes.
The multivariable adjusted hazard ratio (HR) of type 2 diabetes was 6.52 (95% confidence interval [CI] 5.73–7.43) among women with GDM compared to women without GDM.
Stratification by age, race, and body mass index (BMI) gave similar results.
Compared with African American and white women without a history of GDM, the relative risk for type 2 diabetes was higher in African American women than in white women with a history of GDM.
Compared with non–GDM women compartments, GDM women after delivery for <1, 1.0–3.9, 4.0–5.9, 6.0–7.9, 8–9.9, and ≤10.0 years had 4.00, 5.44, 4.26, 3.16, 4.49, and 4.17 times higher risk of having type 2 diabetes, respectively.
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