Diagnostic and therapeutic dilemma associated with atypical glandular cells on liquid-based cervical cytology

Cytopathology, 05/15/2012

This study confirmed significant levels of high–grade disease in women referred to colposcopy with atypical glandular cells on cytology. Concerns about undetected endocervical disease resulted in high levels of negative excisional biopsies. Alternative strategies, including endometrial sampling, human papillomavirus testing and discussion at clinicopathological meeting, should be considered.

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