The predominance of Th17 lymphocytes and decreased number and function of Treg cells in preeclampsia

Journal of Reproductive Immunology, 02/24/2012

The results suggest up–regulation of the Th17 immune response in preeclampsia. The decreased number and function of Treg cells may be responsible for activating the inflammatory response characteristic of this disorder. In preeclampsia, the predominance of Th17 immunity could act through modulating the Th1/Th2 immune balance.

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