Obstetrics & Gynecology News & Articles

1 Imbalance in serum soluble CD30/CD30L and CD40/CD40L systems are associated with ovarian tumors Human Immunology, February 18, 2013
Mielczarek-Palacz A et al. - The aim of the study was to examine the concentrations of the soluble receptors and their ligands of CD30/CD30L and CD40/CD40L systems in the serum of women with ovarian tumor and in the ovarian cyst fluid of women with cystadenoma serosum. Measurement of studied parameter concentrations in serum of women with ovarian tumors has been suggested to be a potential tool in monitoring of inflammatory. Evaluation of sCD30, sCD30L and sCD40 might be an early ...

2 Apolipoprotein concentrations are elevated in malignant ovarian cyst fluids suggesting that lipoprotein metabolism is dysregulated in epithelial ovarian cancer Cancer Investigation, May 22, 2013
Podzielinski I et al. - SELDI-TOF MS analysis of ovarian cyst fluids revealed that peaks m/z 8696 and 8825 discriminate malignant, borderline, and benign tumors. The data suggest that lipoprotein metabolism is dysregulated in ovarian cancer and that apoA2 and apoE warrant further investigation as ovarian tumor biomarkers.

3 Prospective assessment of the impact of endometriomas and their removal on ovarian reserve and determinants of the rate of decline in ovarian reserve Human Reproduction, April 30, 2013
Uncu G. et al. - This study aims to investigates whether the presence of endometriomas and their laparoscopic excision lead to a decrease in ovarian reserve as assessed by serum anti-Müllerian hormone (AMH) levels. No previous comparison of serum AMH levels between women with and without endometrioma has been reported. However, studies have suggested a decline in serum AMH levels 1–3 months after endometrioma excision but long-term data are needed. It was concluded that ...

4 Twisted benign ovarian teratoma presenting with pain and generalized pruritus: a case report Journal of Medical Case Reports, May 14, 2013
Deen R et al. - cystic ovarian teratomas comprise 20% of all ovarian neoplasms, and are commonly encountered in patients between 20 and 40 years of age. Although these cysts are usually asymptomatic, the authors present the case of a patient whose cyst resulted in pruritus and abdominal pain. An unusual case of torsion of an ovarian teratoma presenting with abdominal pain and generalized pruritus, believed to be due to an antibody-mediated response, was resolved after surgical ...

5 A rare cause for a neonatal cystic abdominal mass Journal of Minimally Invasive Gynecology, May 22, 2013
Castellani C et al. - Intrauterine ovarian torsion is a rare event, but it is a possible cause for unilateral ovarian aplasia. Most commonly the ovary undergoes autolysis after torsion so that no tissue or remnants can be discovered on the involved side. Authors report a rare case of unilateral intrauterine torsion followed by autoamputation and abdominal reimplantation resulting in an intra-abdominal complex cystic mass with a review of the literature.

6 Folate receptor alpha (FRA) expression remains unchanged in epithelial ovarian and endometrial cancer after chemotherapy Gynecologic Oncology, April 9, 2013
Despierre E et al. - This study shows no significant difference in FRA expression after chemotherapy, strengthening the rationale for FRA targeted diagnostics and therapeutics in FRA expressing tumors, whether newly diagnosed or at recurrence. Methods FRA staining was evaluated by immunohistochemistry, using MAb 26B3, in 81 patients (41 EOCs and 40 ECs) and 17 control tissues (5 benign ovarian cysts, 5 normal ovarian, and 7 normal endometrial tissues). Chemotherapy effect was ...

7 A Case of Late-Onset Leukoencephalopathy, Calcifications, and Cysts Presenting with Intracerebral Hemorrhage Resembling a Neoplasm Cerebrovascular Diseases, April 30, 2013
Banks GP et al. - A 71-year-old woman with a past history of hypertension, prior ischemic stroke with mild residual left hemiparesis 6 years prior and poorly differentiated ovarian carcinoma in remission for 18 years presented with subacute worsening left hemiparesis and headache for 3 weeks.

8 Adverse events are rare among adults 50 years of age and younger with flank pain when abdominal computed tomography is not clinically indicated according to the emergency physician Canadian Journal of Emergency Medicine, May 3, 2013
Epstein N et al. – Many emergency physicians (EPs) order “confirmatory” abdominal computed tomography (CT) in young flank pain patients, despite a high clinical suspicion of renal colic and the risk of radiation exposure. The authors measured the adverse outcome rate among flank pain patients identified as not requiring abdominal CT by the EP on a data form, regardless of whether CT was eventually ordered. The secondary objective was to describe diagnoses other than renal colic identified by ...