Herbal preparations for uterine fibroids
Cochrane Reviews, May 14, 2013
Liu JP et al. - Uterine fibroids are the most common non-malignant growths in women of childbearing age. They are associated with heavy menstrual bleeding and subfertility. Herbal preparations are commonly used as alternatives to surgical procedures. To evaluate the effectiveness and safety of Chinese herbal medicine for treatment of uterine fibroids. Current evidence does not support or refute the use of herbal preparations for treatment of uterine fibroids due to insufficient ...
Characteristics associated with postoperative diagnosis of adenomyosis or combined adenomyosis with fibroids
International Journal of Gynecology & Obstetrics, May 8, 2013
Jean-Baptiste H et al. - To identify clinical characteristics associated with combined adenomyosis and fibroids and to determine whether preoperative diagnosis by ultrasonography correlates with postoperative diagnosis by pathology. Including the identified variables in the preoperative evaluation of patients with suspicion of fibroids might improve the counseling process and aid the choice of surgical procedure, especially among patients desiring a conservative approach. ...
Self-reported family history of leiomyoma: not a reliable marker of high risk
Annals of Epidemiology , April 30, 2013
Saldana TM et al. - The study aims to examine the importance of self-reported family history of uterine leiomyoma (fibroids) as a marker of risk. Many women may first learn about their family history of fibroids when discussing their own clinical diagnosis with family members. Such bias would invalidate self-reported family history as a predictor of fibroid risk. As new pharmacologic treatments for fibroids are developed, women at high risk of fibroids would benefit from ...
Randomized Comparison of Uterine Artery Embolization (UAE) with Surgical Treatment in Patients with Symptomatic Uterine Fibroids (REST Trial): Subanalysis of 5-Year MRI Findings
Cardiovascular and Interventional Radiology, May 9, 2013
Ananthakrishnan G et al. - To report 5-year contrast-enhanced magnetic resonance imaging findings of the REST trial recruits who underwent either uterine artery embolization (UAE) or myomectomy. There is a further significant reduction in both uterine volume and dominant fibroid diameter between 6 months and 5 years after UAE. Complete fibroid infarction does not translate into total freedom from a subsequent reintervention. New fibroid formation is significantly higher after ...
Magnetic Resonance Imaging-Guided Focused Ultrasound Treatment of Symptomatic Uterine Fibroids: Impact of Technology Advancement on Ablation Volumes in 115 Patients
Investigative Radiology, May 7, 2013
Trumm CG et al. - The aim of this study was to assess the impact of the advanced technology of the new ExAblate 2100 system (Insightec Ltd, Haifa, Israel) for magnetic resonance imaging (MRI)–guided focused ultrasound surgery on treatment outcomes in patients with symptomatic uterine fibroids, as measured by the nonperfused volume ratio. With technological advancement, the outcome of MRI-guided focused ultrasound treatment in terms of the nonperfused volume ratio can be enhanced ...
Uterine fibroids and subfertility: an update on the role of myomectomy
Current Opinion in Obstetrics and Gynecology, May 16, 2013
Brady PC et al. - Submucosal fibroid location and distortion of the endometrial cavity (either submucosal or deeply infiltrating intramural fibroids) are most predictive of impaired fertility and probable benefit of surgical removal, and warrant consideration of myomectomy in the subfertile patient.
Prophylactic use of levonorgestrel-releasing intrauterine system in women with breast cancer treated with tamoxifen: a randomized controlled trial
Obstetrics and Gynecology, May 13, 2013
Wong AWY et al. - This study aimed to estimate the rate of endometrial pathology with the prophylactic use of levonorgestrel-releasing intrauterine system in women with breast cancer treated with tamoxifen. Prophylactic levonorgestrel-releasing intrauterine system prevents de novo endometrial polyps in women using tamoxifen. However, its role in the prevention of endometrial hyperplasia and adenocarcinoma as well as its effect on risk of breast cancer recurrence remain ...
Feasibility of a new two-step procedure for office hysteroscopic resection of submucous myomas: results of a pilot study
European Journal of Obstetrics & Gynecology and Reproductive Biology, February 1, 2013
Haimovich S et al. - This study aimed to assess the feasibility of a new two-step technique for office hysteroscopic resection of submucous myomas. The new two-step hysteroscopic myomectomy carried out as an outpatient procedure and without anesthesia is feasible for the excision of symptomatic submucous fibroids. Methods Between January 2010 and December 2011, all consecutive patients of reproductive age with symptomatic lesions sonographically diagnosed as ...
Gene expression analysis reveals an angiogenic profile in uterine leiomyoma pseudocapsule
Molecular Human Reproduction, February 6, 2013
Tommaso SD et al. - In this study, quantitative RT-PCR (qRT-PCR) analysis was performed on 18 matched PC, UL and UM specimens and results showed that the PC displays a specific gene expression profile. This data demonstrate that the specific expression pattern observed in the PC could be the response of the uterine wall's smooth cells to the tension imposed by the tumor. As a consequence, a neo-vascular structure is generated involving regenerative processes. For these ...
Therapeutic Ultrasound Welcomes First Open Access Journal
Imaging Economics, May 10, 2013
Focused ultrasound has the potential to be an alternative or complement for radiation therapy, the means to dissolve blood clots, and a way to deliver drugs in extremely high concentrations to a precise point in the body. It has the potential to treat a variety of serious medical disorders, including cancer, uterine fibroids, essential tremor, Parkinson's disease, epilepsy, and neuropathic pain.