EZH2 predicts poor prognosis in cervical cancer
As reported in the International Journal of Gynecological Pathology, the expression of enhancer zeste homolog (EZH)2 is associated with clinical stage, histologic differentiation, depth of infiltration, and lymph node metastasis in patients with cervical cancer; moreover, EZH2 expression is associated with a decreased OS. Expression of EZH2 was demonstrated in 10% of normal cervical specimens, 52% of LGSIL specimens, 64% of HGSIL specimens, and 68.3% of cervical cancer specimens.
Pre-operative tranexamic acid reduces blood loss in ovarian cancer patients
As reported in ACTA Obstetricia et Gynecologica, a single pre-operative dose of tranexamic acid (15 mg/kg) significantly reduced blood loss (520 cc vs 730 cc) and the transfusion rate (30% vs. 44%) in ovarian cancer patients (n=100) undergoing radical debulking.
Apelin levels correlate with insulin sensitivity and lipid profile in PCOS
As reported in Seizure: European Journal of Epilepsy, patients with epilepsy (n=3182) have a 3-fold increased risk for cerebral stroke. The risk was highest in the 20-39 year age group and those taking high doses of anti-epileptic medications.