Atypical glandular cells associated with increased risk of extrauterine disease
As reported in the International Journal of Gynecologic Cancer, abnormal cervical cytology (atypical glandular cells [AGC] or malignant cells [MC]) on pre-operative cervical cytology predicts extrauterine disease (OR=4.78) and high intermediate risk disease (OR=8.41) in patients with endometrial adenocarcinoma (n=563). In patients with an elevated CA-125 level, the OR for extrauterine and high intermediate risk disease was 13.3 and 5.83, respectively.
Pre-operative tranexamic acid reduces blood loss in ovarian cancer patients
As reported in ACTA Obstetricaet Gynecologica, a single pre-operative dose of tranexamic acid (15 mg/kg) significantly reduced blood loss (520 cc vs 730 cc) and the transfusion rate (30% vs. 44%) in ovarian cancer patients (n=100) undergoing radical debulking.
Apelin levels correlate with insulin sensitivity and lipid profile in PCOS
As reported in Seizure: European Journal of Epilepsy, patients with epilepsy (n=3182) have a 3-fold increased risk for cerebral stroke. The risk was highest in the 20-39 year age group and those taking high doses of anti-epileptic medications.