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See Latest ArticlesGonadotropin releasing hormone antagonists suppress aromatase and anti-Mullerian hormone expression in human granulosa cells
Fertility and Sterility, 11/10/09
Winkler N et al. – GnRH–ANTs, in addition to their central suppressive effects on the pituitary, may have a direct effect on ovarian granulosa cells with inhibition of aromatase and AMH expression. Furthermore, the inhibitory effect could be mediated via suppression of SF–1 and LRH–1, and may play a role in estrogen–mediated ovarian folliculogenesis.
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