Ob/Gyn Medical News about Pre-Eclampsia

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A Randomised, Double-Blinded, Placebo-Controlled Study of the Phosphodiesterase Type 5 Inhibitor Sildenafil for the Treatment of Preeclampsia
Hypertension in Pregnancy, 10/30/09

Samangaya RA et al. – The authors have safely conducted a clinical trial of a drug not routinely used during pregnancy. Sildenafil in the escalating dose regimen 20–80 mg tid was well tolerated, with no increase in maternal or fetal morbidity or mortality but did not prolong pregnancy duration in women with preeclampsia.

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Maternal Circulating TNF-alpha Levels are Highly Correlated with IL-10 Levels, but not IL-6 and IL-8 Levels, in Women with Pre-Eclampsia
American Journal of Reproductive Immunology, 10/13/09 Relevance Score: 84%

Genetic polymorphisms in DNA repair gene APE1, XRCC1 and XPD and the risk of pre-eclampsia
European Journal of Obstetrics & Gynecology and Reproductive Biology, 10/09/09 Relevance Score: 84%

Soluble and Membranous Vascular Endothelial Growth Factor Receptor-2 in Pregnancies Complicated by Pre-Eclampsia
Yonsei Medical Journal, 10/29/09 Relevance Score: 82%

A Meta-Analysis on the Efficacy and Safety of Combined Vitamin C and E Supplementation in Preeclamptic Women
Hypertension in Pregnancy, 10/30/09 Relevance Score: 80%

Preeclampsia and Risk of Developing Subsequent Diabetes
Hypertension in Pregnancy, 10/30/09 Relevance Score: 80%