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Evidence that Corticotropin-Releasing Hormone Modulates Myometrial Contractility during Human Pregnancy
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Tyson EK et al. – PDE inhibition potentiates CRH and salbutamol–induced relaxation. Up–regulation of PDEs, through chronic cAMP elevation by CRH, could provide a mechanism for down–regulation of agonist–stimulated–cAMP pathways at term.
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