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Characterizing the HER2/neu Status and Metastatic Potential of Breast Cancer Stem/Progenitor Cells
Annals of Surgical Oncology, 10/20/09
Pommier SJ et al. – Breast cancer stem/progenitor cell populations differ in tumor–initiating potential but are not solely responsible for metastasis. Cancer stem/progenitor cells are less polyploid than cancer cells in general and may not be HER2/neu amplified. In normal breast tissue, breast stem/progenitor cell–like populations are present.
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