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Impact of the size of zona pellucida thinning area on vitrified-warmed cleavage-stage embryo transfers: a prospective, randomized study
Journal of Assisted Reproduction and Genetics, 10/20/09

Hiraoka K et al. – The results of the investigation show that, in vitrified–warmed embryo transfers at the cleavage–stage, the size of zona pellucida thinning area by laser assisted hatching impacts the rate of clinical pregnancy and implantation and that half of zona pellucida thinning significantly increases both of these results compared with quarter of zona pellucida thinning.

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