Ob/Gyn Medical News about Hypersensitivity Vulvodynia

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Allergic Reactions and Risk of Vulvodynia
Annals of Epidemiology , 10/13/09

Harlow BL et al. – An altered immuno–inflammatory response to environmentally induced allergic reactions may predispose women to the development of vulvodynia or may be markers of an already heightened immuno–inflammatory response.

Methods

The authors studied 239 women with and 239 women without vulvodynia to assess the influence of self–reported allergic reactions antecedent to first development of vulvar pain symptoms among cases, and a matched reference age among controls.

Results

Women with self–reported hives prior to first report of vulvar pain or reference age among controls were 2.5 times more likely to develop vulvodynia.
Those reporting a history of allergic reactions to insect bites were 2.1 times more likely, and those reporting a history of seasonal allergies were 2.0 times more likely to develop vulvodynia.
Findings were similar in a restricted subset of clinically confirmed cases and matched controls.

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