Ob/Gyn Medical News about Alendronate Postmenopause Women

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Upper gastrointestinal tolerability of alendronate sodium monohydrate 10 mg once daily in postmenopausal women: A 12-week, randomized, double-blind, placebo-controlled, exploratory study
Clinical Therapeutics, 10/15/09

Adachi JD et al. – In these postmenopausal women who received ALN monohydrate or placebo, upper GI AEs were common (20.4%–22.7%). The proportion of patients who experienced upper GI AEs considered drug related or that led to discontinuation was appar– ently greater with ALN monohydrate compared with placebo.

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Serum cathepsin K as a marker of bone metabolism in postmenopausal women treated with alendronate
Maturitas, 11/12/09 Relevance Score: 81%

Oestrogen plus progestin and lung cancer in postmenopausal women (Womens Health Initiative trial): a post-hoc analysis of a randomised controlled trial
The Lancet, 10/12/09 Relevance Score: 71%

Bone Mineral Density and Serum Levels of Soluble Tumor Necrosis Factors, Estradiol, and Osteoprotegerin in Postmenopausal Women with Cirrhosis after Viral Hepatitis
Journal of Clinical Endocrinology and Metabolism, 11/18/09 Relevance Score: 70%

Validation of a Women's Sexual Interest Diagnostic Interview—Short Form (WSID-SF) and a Daily Log of Sexual Activities (DLSA) in Postmenopausal Women with Hypoactive Sexual Desire Disorder
The Journal of Sexual Medicine, 10/30/09 Relevance Score: 69%

Alcohol consumption and the risk of coronary heart disease in postmenopausal women with diabetes: Women’s Health Initiative Observational Study
European Journal of Nutrition, 10/20/09 Relevance Score: 69%