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XIAP gene downregulation by small interfering RNA inhibits proliferation, induces apoptosis, and reverses the cisplatin resistance of ovarian carcinoma
European Journal of Obstetrics & Gynecology and Reproductive Biology , 10/09/09
Ma JJ et al. – XIAP gene RNAi inhibited the proliferation of ovarian carcinoma cells and caused cells to be more sensitive to cisplatin through the reduction of its mRNA and protein. These results suggest that XIAP is an ovarian cancer–related gene and that XIAP is a potential target for therapeutic anti–cancer drugs.
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