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A hypothesis and model of reduced fetal movement as a common pathogenetic mechanism in clubfoot
Medical Hypotheses, 09/30/09
Hester TW et al. – The authors propose that the underlying unifying factor in all cases of clubfoot is a lack of fetal movement. Fetal movement is a key developmental signal in the development of joints, and we suggest that this applies to the morphogenesis of the forefoot. Theories exist to explain specific individual features of clubfoot in certain cases and to explain experimental studies, however no common final pathway has been described.
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