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In vitro post-meiotic germ cell development from human embryonic stem cells
Human Reproduction, 09/24/09
Aflatoonian B al. – HESCs can form PGCs and post–meiotic spermatids in vitro, however, there remains doubt about oocyte development. Levels of steroid hormones produced by EBs were significant when compared with known values for a similar quantity of human testis, suggesting that hESC may intrinsically create a favourable hormonal niche for spermatogenesis.
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