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Urine HPV-DNA detection for cervical cancer screening: Prospects and prejudices
Journal of Obstetrics and Gynaecology, 09/21/09
Sehgal A et al. – The review process consisted of assembling facts and analysing the published literature on the following facts: anatomical considerations of the lower genital and the lower urinary tract, biological behaviour of HPV and its shedding behaviour, technical issues regarding sample collection, processing and HPV–DNA assay systems, concordance rates of HPV–DNA detection and their type specificity in the paired samples (urine and cervical scrapes) obtained in different clinico–epidemiological settings and comparative detection rates of HSILs in the paired samples.
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