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Chambers DG et al. – The retrospective study showed an association between perioperative administration of misoprostol, reduced difficulty for operators, and reduced demand for postoperative care. The regimen associated with the greatest reduction in difficult cervical dilatations and postoperative consultations was 200microg of oral misoprostol 3 hours preoperatively plus 200microg of misoprostol vaginally at the end of the surgical procedure.

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