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Rosano GMC et al. – Clinical judgement, choice of the right dose and estrogen/progestin combination are of pivotal importance to maximize the beneficial effect of estrogen or estrogen–progestin replacement therapy, especially if given within a reasonably short time after the menopause to those women that need this therapy for the relief of menopausal symptoms. In these women, continuation of estrogen or estrogen–progestin replacement therapy may be beneficial.

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