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Human decidual stromal cells suppress cytokine secretion by allogenic CD4+ T cells via PD-1 ligand interactions
Human Reproduction, 09/04/09

Schust DJ et al. – The authors findings support the categorization of human DSCs as non–professional APCs and suggest that PD–1 ligands on DSCs, together with major histocompatibility complex class II, may play a crucial role in the regulation of decidual CD4+ T cell cytokine production. This helps to maintain a balanced cytokine milieu at the feto–maternal interface.

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