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Administration of clomiphene citrate in patients with polycystic ovary syndrome, without inducing withdrawal bleeding, achieves comparable treatment characteristics and outcome
Fertility and Sterility, 09/08/09

Farhi J et al. – The effect of random timing of the start of clomiphene citrate (CC) treatment in anovulatory patients with polycystic ovary syndrome on treatment characteristics and outcome, with no regard to time of menstruation, the authors studied 291 women in their first CC treatment cycle. Duration of treatment was shorter by 2 days and number of leading follicles was higher when treatment was started late (7–29 days from starting a bleed, as compared with day 5), but no effect of starting day was observed on response rate to CC, maximal E2 level, endometrial thickness, and pregnancy rate.

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